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Comparative characterisation of two nitroreductases from Giardia lamblia as potential activators of nitro compounds
Giardia lamblia is a protozoan parasite that causes giardiasis, a diarrhoeal disease affecting humans and various animal species. Nitro drugs such as the nitroimidazole metronidazole and the nitrothiazolide nitazoxanide are used for treatment of giardiasis. Nitroreductases such as GlNR1 and GlNR2 ma...
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| Publicado no: | Int J Parasitol Drugs Drug Resist |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4813764/ https://ncbi.nlm.nih.gov/pubmed/27099829 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpddr.2015.03.001 |
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