Docosahexaenoic acid inhibits melanin synthesis in murine melanoma cells in vitro through increasing tyrosinase degradation

AIM: To investigate the effects of docosahexaenoic acid (DHA) on melanin synthesis and related regulatory mechanisms. METHODS: B16F10 mouse melanoma cells were exposed to DHA for 3 d, and melanin content and tyrosinase activity were measured. Western blot analysis was used to analyze the protein lev...

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Vydáno v:Acta Pharmacol Sin
Hlavní autoři: Balcos, Marie Carmel, Kim, Su Yeon, Jeong, Hyo-soon, Yun, Hye-young, Baek, Kwang Jin, Kwon, Nyoun Soo, Park, Kyoung-chan, Kim, Dong-seok
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2014
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4813719/
https://ncbi.nlm.nih.gov/pubmed/24562306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2013.174
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