Lactoferrin inhibits apoptosis through insulin-like growth factor I in primary rat osteoblasts

AIM: Excessive apoptosis of osteoblasts is the major cause of low bone mass, and bovine lactoferrin (bLF), an iron-binding glycoprotein, might protect osteoblastic cells from apoptosis induced by serum withdrawal. The aim of this study was to elucidate the mechanisms underlying the anti-apoptotic ac...

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Publicat a:Acta Pharmacol Sin
Autors principals: Hou, Jian-ming, Chen, En-yu, Wei, Shi-chao, Lin, Fan, Lin, Qing-ming, Lan, Xu-hua, Xue, Ying, Wu, Man
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2014
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4813718/
https://ncbi.nlm.nih.gov/pubmed/24562308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2013.173
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