Palmitic acid induces autophagy in hepatocytes via JNK2 activation

AIM: Free fatty acid-induced lipotoxicity plays a crucial role in the progression of nonalcoholic fatty liver disease (NAFLD). In the present study we investigated the effects of a high-fat diet and free fatty acids on the autophagic process in hepatocytes in vivo and in vitro and the underlying mec...

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Detalhes bibliográficos
Publicado no:Acta Pharmacol Sin
Main Authors: Tu, Qian-qian, Zheng, Rui-ying, Li, Juan, Hu, Liang, Chang, Yan-xin, Li, Liang, Li, Min-hong, Wang, Ruo-yu, Huang, Dan-dan, Wu, Meng-chao, Hu, He-ping, Chen, Lei, Wang, Hong-yang
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4813717/
https://ncbi.nlm.nih.gov/pubmed/24608675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2013.170
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