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GPR21 KO mice demonstrate no resistance to high fat diet induced obesity or improved glucose tolerance

Gpr21 KO mice generated with Gpr21 KO ES cells obtained from Deltagen showed improved glucose tolerance and insulin sensitivity when fed a high fat diet. Further mRNA expression analysis revealed changes in Rabgap1 levels and raised the possibility that Rabgap1 gene may have been modified. To assess...

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Détails bibliographiques
Publié dans:F1000Res
Auteurs principaux: Wang, Jinghong, Pan, Zheng, Baribault, Helene, Chui, Danny, Gundel, Caroline, Véniant, Murielle
Format: Artigo
Langue:Inglês
Publié: F1000Research 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4813635/
https://ncbi.nlm.nih.gov/pubmed/27081476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/f1000research.7822.2
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