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Squamous Cell Carcinoma-related Oncogene (SCCRO) Family Members Regulate Cell Growth and Proliferation through Their Cooperative and Antagonistic Effects on Cullin Neddylation

SCCRO (squamous cell carcinoma-related oncogene; also known as DCUN1D1) is a highly conserved gene that functions as an E3 in neddylation. Although inactivation of SCCRO in yeast results in lethality, SCCRO(−/−) mice are viable. The exclusive presence of highly conserved paralogues in higher organis...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Fu, Weimin, Sun, Joanne, Huang, Guochang, Liu, Jeffrey C., Kaufman, Andrew, Ryan, Russell J. H., Ramanathan, Suresh Y., Venkatesh, Tadmiri, Singh, Bhuvanesh
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4813546/
https://ncbi.nlm.nih.gov/pubmed/26792857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.692756
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