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HIV-1 Nef-associated Factor 1 Enhances Viral Production by Interacting with CRM1 to Promote Nuclear Export of Unspliced HIV-1 gag mRNA

HIV-1 depends on host-cell-encoded factors to complete its life cycle. A comprehensive understanding of how HIV-1 manipulates host machineries during viral infection can facilitate the identification of host targets for antiviral drugs or gene therapy. The cellular protein Naf1 (HIV-1 Nef-associated...

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Dettagli Bibliografici
Pubblicato in:J Biol Chem
Autori principali: Ren, Xiao-Xin, Wang, Hai-Bo, Li, Chuan, Jiang, Jin-Feng, Xiong, Si-Dong, Jin, Xia, Wu, Li, Wang, Jian-Hua
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4813482/
https://ncbi.nlm.nih.gov/pubmed/26733199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.706135
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