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Quetiapine and its metabolite norquetiapine: translation from in vitro pharmacology to in vivo efficacy in rodent models

BACKGROUND AND PURPOSE: Quetiapine has a range of clinical activity distinct from other atypical antipsychotic drugs, demonstrating efficacy as monotherapy in bipolar depression, major depressive disorder and generalized anxiety disorder. The neuropharmacological mechanisms underlying this clinical...

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Podrobná bibliografie
Vydáno v:Br J Pharmacol
Hlavní autoři: Cross, A J, Widzowski, D, Maciag, C, Zacco, A, Hudzik, T, Liu, J, Nyberg, S, Wood, M W
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4813385/
https://ncbi.nlm.nih.gov/pubmed/26436896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13346
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