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KMT2D regulates specific programs in heart development via histone H3 lysine 4 di-methylation
KMT2D, which encodes a histone H3K4 methyltransferase, has been implicated in human congenital heart disease in the context of Kabuki syndrome. However, its role in heart development is not understood. Here, we demonstrate a requirement for KMT2D in cardiac precursors and cardiomyocytes during cardi...
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| Publicado no: | Development |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Company of Biologists Ltd
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4813342/ https://ncbi.nlm.nih.gov/pubmed/26932671 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.132688 |
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