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A gradient of maternal Bicaudal-C controls vertebrate embryogenesis via translational repression of mRNAs encoding cell fate regulators

Vertebrate Bicaudal-C (Bicc1) has important biological roles in the formation and homeostasis of multiple organs, but direct experiments to address the role of maternal Bicc1 in early vertebrate embryogenesis have not been reported. Here, we use antisense phosphorothioate-modified oligonucleotides a...

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Publicado en:Development
Autores principales: Park, Sookhee, Blaser, Susanne, Marchal, Melissa A., Houston, Douglas W., Sheets, Michael D.
Formato: Artigo
Lenguaje:Inglês
Publicado: The Company of Biologists Ltd 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4813341/
https://ncbi.nlm.nih.gov/pubmed/26811381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.131359
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