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A Comparative Study of Molecular Structure, pKa, Lipophilicity, Solubility, Absorption and Polar Surface Area of Some Antiplatelet Drugs

Theoretical chemistry methods have been used to study the molecular properties of antiplatelet agents (ticlopidine, clopidogrel, prasugrel, elinogrel, ticagrelor and cangrelor) and several thiol-containing active metabolites. The geometries and energies of most stable conformers of these drugs have...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Int J Mol Sci
Prif Awduron: Remko, Milan, Remková, Anna, Broer, Ria
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: MDPI 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4813244/
https://ncbi.nlm.nih.gov/pubmed/27007371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms17030388
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