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Tamoxifen Treatment of Breast Cancer Cells: Impact on Hedgehog/GLI1 Signaling

The selective estrogen receptor (ER) modulator tamoxifen (TAM) has become the standard therapy for the treatment of ER+ breast cancer patients. Despite the obvious benefits of TAM, a proportion of patients acquire resistance to treatment, and this is a significant clinical problem. Consequently, the...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Villegas, Victoria E., Rondón-Lagos, Milena, Annaratone, Laura, Castellano, Isabella, Grismaldo, Adriana, Sapino, Anna, Zaphiropoulos, Peter G.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4813171/
https://ncbi.nlm.nih.gov/pubmed/26927093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms17030308
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