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Reduced Connexin26 in the Mature Cochlea Increases Susceptibility to Noise-Induced Hearing Loss in Mice

Connexin26 (Cx26, encoded by GJB2) mutations are the most common cause of non-syndromic deafness. GJB2 is thought to be involved in noise-induced hearing loss (NIHL). However, the role of Cx26 in NIHL is still obscure. To explore the association between Cx26 and NIHL, we established a Cx26 knockdown...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Int J Mol Sci
Hauptverfasser: Zhou, Xing-Xing, Chen, Sen, Xie, Le, Ji, Yu-Zi, Wu, Xia, Wang, Wen-Wen, Yang, Qi, Yu, Jin-Tao, Sun, Yu, Lin, Xi, Kong, Wei-Jia
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4813165/
https://ncbi.nlm.nih.gov/pubmed/26927086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms17030301
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