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Changes in Neuronal Excitability by Activated Microglia: Differential Na(+) Current Upregulation in Pyramid-Shaped and Bipolar Neurons by TNF-α and IL-18

Microglia are activated during pathological events in the brain and are capable of releasing various types of inflammatory cytokines. Here, we demonstrate that the addition of 5% microglia activated by 1 μg/ml lipopolysaccharides (LPS) to hippocampal cultures upregulates Na(+) current densities (I(N...

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Bibliografische gegevens
Gepubliceerd in:Front Neurol
Hoofdauteurs: Klapal, Lars, Igelhorst, Birte A., Dietzel-Meyer, Irmgard D.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2016
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4812774/
https://ncbi.nlm.nih.gov/pubmed/27065940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fneur.2016.00044
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