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Single Molecule Hydrodynamic Separation Allows Sensitive and Quantitative Analysis of DNA Conformation and Binding Interactions in Free Solution

Limited tools exist that are capable of monitoring nucleic acid conformations, fluctuations, and distributions in free solution environments. Single molecule free solution hydrodynamic separation enables the unique ability to quantitatively analyze nucleic acid biophysics in free solution. Single mo...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Friedrich, Sarah M., Liu, Kelvin J., Wang, Tza-Huei
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4812671/
https://ncbi.nlm.nih.gov/pubmed/26684193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.5b10983
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