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MicroRNA-186 targets Yes-associated protein 1 to inhibit Hippo signaling and tumorigenesis in hepatocellular carcinoma

Liver cancer, particularly hepatocellular carcinoma (HCC), is one of leading causes of cancer-related mortality worldwide. Upregulation of the evolutionary conserved Hippo signaling pathway has been observed in HCC patients, and Yes-associated protein 1 (YAP1) has been reported to play a key role in...

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Bibliographic Details
Published in:Oncol Lett
Main Authors: RUAN, TINGYAN, HE, XIAOTING, YU, JUN, HANG, ZHIQIANG
Format: Artigo
Language:Inglês
Published: D.A. Spandidos 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4812570/
https://ncbi.nlm.nih.gov/pubmed/27073580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2016.4312
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