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Probing Structural Dynamics and Topology of the KCNE1 Membrane Protein in Lipid Bilayers via Site-Directed Spin Labeling and Electron Paramagnetic Resonance Spectroscopy

KCNE1 is a single transmembrane protein that modulates the function of voltage-gated potassium channels, including KCNQ1. Hereditary mutations in the genes encoding either protein can result in diseases such as congenital deafness, long QT syndrome, ventricular tachyarrhythmia, syncope, and sudden c...

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Detalhes bibliográficos
Publicado no:Biochemistry
Main Authors: Sahu, Indra D., Craig, Andrew F., Dunagan, Megan M., Troxel, Kaylee R., Zhang, Rongfu, Meiberg, Andrew G., Harmon, Corrinne N., McCarrick, Robert M., Kroncke, Brett M., Sanders, Charles R., Lorigan, Gary A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4812432/
https://ncbi.nlm.nih.gov/pubmed/26418890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.5b00505
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