Phosphorylated 4EBP1 is associated with tumor progression and poor prognosis in Xp11.2 translocation renal cell carcinoma

Two main signaling pathways, PI3K-AKT-mTOR and RAS-MAPK, are involved in transmitting the proliferative signals which play critical roles in human cancers. However, the functions of these pathways in Xp11.2 RCC remain undefined. This study aimed to explore the expression of mTOR and MAPK cascades in...

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發表在:Sci Rep
Main Authors: Qu, Yuanyuan, Zhao, Rui, Wang, Hongkai, Chang, Kun, Yang, Xiaoqun, Zhou, Xiaoyan, Dai, Bo, Zhu, Yao, Shi, Guohai, Zhang, Hailiang, Ye, Dingwei
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2016
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4812307/
https://ncbi.nlm.nih.gov/pubmed/27026382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep23594
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