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Human cytomegalovirus gH stability and trafficking are regulated by ER-associated degradation and transmembrane architecture

The prototypic betaherpesvirus human cytomegalovirus (CMV) establishes life-long persistence within its human host. While benign in healthy individuals, CMV poses a significant threat to the immune compromised, including transplant recipients and neonates. The CMV glycoprotein complex gH/gL/gO media...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Gardner, Thomas J., Hernandez, Rosmel E., Noriega, Vanessa M., Tortorella, Domenico
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4812245/
https://ncbi.nlm.nih.gov/pubmed/27026399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep23692
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