Insulin-like peptide 5 is a microbially regulated peptide that promotes hepatic glucose production

OBJECTIVE: Insulin-like peptide 5 (INSL5) is a recently identified gut hormone that is produced predominantly by L-cells in the colon, but its function is unclear. We have previously shown that colonic expression of the gene for the L-cell hormone GLP-1 is high in mice that lack a microbiota and thu...

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Bibliografiska uppgifter
I publikationen:Mol Metab
Huvudupphovsmän: Lee, Ying Shiuan, De Vadder, Filipe, Tremaroli, Valentina, Wichmann, Anita, Mithieux, Gilles, Bäckhed, Fredrik
Materialtyp: Artigo
Språk:Inglês
Publicerad: Elsevier 2016
Ämnen:
Original Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4811983/
https://ncbi.nlm.nih.gov/pubmed/27069866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2016.01.007
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