Targeted Editing of Myostatin Gene in Sheep by Transcription Activator-like Effector Nucleases

Myostatin (MSTN) is a secreted growth factor expressed in skeletal muscle and adipose tissue that negatively regulates skeletal muscle mass. Gene knockout of MSTN can result in increasing muscle mass in sheep. The objectives were to investigate whether myostatin gene can be edited in sheep by transc...

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Pubblicato in:Asian-Australas J Anim Sci
Autori principali: Zhao, Xinxia, Ni, Wei, Chen, Chuangfu, Sai, Wujiafu, Qiao, Jun, Sheng, Jingliang, Zhang, Hui, Li, Guozhong, Wang, Dawei, Hu, Shengwei
Natura: Artigo
Lingua:Inglês
Pubblicazione: Asian-Australasian Association of Animal Production Societies (AAAP) and Korean Society of Animal Science and Technology (KSAST) 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4811794/
https://ncbi.nlm.nih.gov/pubmed/26950874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5713/ajas.15.0041
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