The nucleolar protein NIFK promotes cancer progression via CK1α/β-catenin in metastasis and Ki-67-dependent cell proliferation

Nucleolar protein interacting with the FHA domain of pKi-67 (NIFK) is a Ki-67-interacting protein. However, its precise function in cancer remains largely uninvestigated. Here we show the clinical significance and metastatic mechanism of NIFK in lung cancer. NIFK expression is clinically associated...

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Enregistré dans:
Détails bibliographiques
Publié dans:eLife
Auteurs principaux: Lin, Tsung-Chieh, Su, Chia-Yi, Wu, Pei-Yu, Lai, Tsung-Ching, Pan, Wen-An, Jan, Yi-Hua, Chang, Yu-Chang, Yeh, Chi-Tai, Chen, Chi-Long, Ger, Luo-Ping, Chang, Hong-Tai, Yang, Chih-Jen, Huang, Ming-Shyan, Liu, Yu-Peng, Lin, Yuan-Feng, Shyy, John Y-J, Tsai, Ming-Daw, Hsiao, Michael
Format: Artigo
Langue:Inglês
Publié: eLife Sciences Publications, Ltd 2016
Sujets:
Cell Biology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4811767/
https://ncbi.nlm.nih.gov/pubmed/26984280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.11288
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