Astrocyte-derived pentraxin 3 supports blood-brain barrier integrity under acute phase of stroke

BACKGROUND AND PURPOSE: Pentraxin 3 (PTX3) is released upon inflammatory responses in many organs. However, roles of PTX3 in brain are still mostly unknown. Here we asked whether and how PTX3 contributes to blood-brain barrier (BBB) dysfunction during the acute phase of ischemic stroke. METHODS: In...

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Publicado en:Stroke
Main Authors: Shindo, Akihiro, Maki, Takakuni, Mandeville, Emiri T., Liang, Anna C., Egawa, Naohiro, Itoh, Kanako, Itoh, Naoki, Borlongan, Mia, Holder, Julie C., Chuang, Tsu Tshen, McNeish, John D., Tomimoto, Hidekazu, Lok, Josephine, Lo, Eng H., Arai, Ken
Formato: Artigo
Idioma:Inglês
Publicado: 2016
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4811738/
https://ncbi.nlm.nih.gov/pubmed/26965847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.115.012133
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