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Increased IGFBP-1 phosphorylation in response to leucine deprivation is mediated by CK2 and PKC
Insulin-like growth factor binding protein-1 (IGFBP-1), secreted by fetal liver, is a key regulator of IGF-I bioavailability and fetal growth. IGFBP-1 phosphorylation decreases IGF-I bioavailability and diminishes its growth-promoting effects. Growth-restricted fetuses have decreased levels of circu...
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| Udgivet i: | Mol Cell Endocrinol |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4811673/ https://ncbi.nlm.nih.gov/pubmed/26733150 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mce.2015.12.006 |
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