Comparative Analysis of Matrix Metalloproteinase Family Members Reveals That MMP9 Predicts Survival and Response to Temozolomide in Patients with Primary Glioblastoma

BACKGROUND: Glioblastoma multiform (GBM) is the most common malignant primary brain tumor in adults. Radiotherapy plus concomitant and adjuvant TMZ chemotherapy is the current standard of care for patients with GBM. Matrix metalloproteinases (MMPs), a family of zinc-dependent endopeptidases, are key...

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Veröffentlicht in:PLoS One
Hauptverfasser: Li, Qingbin, Chen, Baoshi, Cai, Jinquan, Sun, Ying, Wang, Guangzhi, Li, Yongli, Li, Ruiyan, Feng, Yan, Han, Bo, Li, Jianlong, Tian, Yu, Yi, Liye, Jiang, Chuanlu
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2016
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4811585/
https://ncbi.nlm.nih.gov/pubmed/27022952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0151815
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