Enhancement of anti-leukemia activity of NK cells in vitro and in vivo by inhibition of leukemia cell-induced NK cell damage

Acute myeloid leukemia (AML) cells induce, in vitro, NK cell abnormalities (NKCAs) including apoptosis and activating receptor down-regulation. The potential negative impact of AML cells on the therapeutic efficacy of NK cell-based strategies prompted us to analyze the mechanisms underlying NKCAs an...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Arriga, Roberto, Caratelli, Sara, Coppola, Andrea, Spagnoli, Giulio Cesare, Venditti, Adriano, Amadori, Sergio, Lanzilli, Giulia, Lauro, Davide, Palomba, Patrizia, Sconocchia, Tommaso, Del Principe, Maria Ilaria, Maurillo, Luca, Buccisano, Francesco, Capuani, Barbara, Ferrone, Soldano, Sconocchia, Giuseppe
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4811516/
https://ncbi.nlm.nih.gov/pubmed/26655503
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