Loss of 11βHSD1 enhances glycolysis, facilitates intrahepatic metastasis, and indicates poor prognosis in hepatocellular carcinoma

11Beta-hydroxysteroid dehydrogenase type 1 (11βHSD1), converting glucocorticoids from hormonally inactive cortisone to active cortisol, plays an essential role in glucose homeostasis. Accumulating evidence suggests that enhanced glycolytic activity is closely associated with postoperative recurrence...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Liu, Xu, Tan, Xiao-long, Xia, Meng, Wu, Chao, Song, Jia, Wu, Jing-jing, Laurence, Arian, Xie, Qing-guo, Zhang, Ming-zhi, Liang, Hui-fang, Zhang, Bi-xiang, Chen, Xiao-ping
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4811515/
https://ncbi.nlm.nih.gov/pubmed/26700460
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