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Low β(2)-adrenergic receptor level may promote development of castration resistant prostate cancer and altered steroid metabolism

The underlying mechanisms responsible for the development of castration-resistant prostate cancer (CRPC) in patients who have undergone androgen deprivation therapy are not fully understood. This is the first study to address whether β(2)-adrenergic receptor (ADRB2)- mediated signaling may affect CR...

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Pubblicato in:Oncotarget
Autori principali: Braadland, Peder Rustøen, Grytli, Helene Hartvedt, Ramberg, Håkon, Katz, Betina, Kellman, Ralf, Gauthier-Landry, Louis, Fazli, Ladan, Krobert, Kurt Allen, Wang, Wanzhong, Levy, Finn Olav, Bjartell, Anders, Berge, Viktor, Rennie, Paul S., Mellgren, Gunnar, Mælandsmo, Gunhild Mari, Svindland, Aud, Barbier, Olivier, Taskén, Kristin Austlid
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4811504/
https://ncbi.nlm.nih.gov/pubmed/26646591
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