NF-Y activates genes of metabolic pathways altered in cancer cells

The trimeric transcription factor NF-Y binds to the CCAAT box, an element enriched in promoters of genes overexpressed in tumors. Previous studies on the NF-Y regulome identified the general term metabolism as significantly enriched. We dissect here in detail the targeting of metabolic genes by inte...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Benatti, Paolo, Chiaramonte, Maria Luisa, Lorenzo, Mariangela, Hartley, John A., Hochhauser, Daniel, Gnesutta, Nerina, Mantovani, Roberto, Imbriano, Carol, Dolfini, Diletta
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4811486/
https://ncbi.nlm.nih.gov/pubmed/26646448
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