Prognostic impact of programmed cell death-1 (PD-1) and PD-ligand 1 (PD-L1) expression in cancer cells and tumor-infiltrating lymphocytes in ovarian high grade serous carcinoma

AIMS: Antibodies targeting the checkpoint molecules programmed cell death 1 (PD-1) and its ligand PD-L1 are emerging cancer therapeutics. We systematically investigated PD-1 and PD-L1 expression patterns in the poor-prognosis tumor entity high-grade serous ovarian carcinoma. METHODS: PD-1 and PD-L1...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Darb-Esfahani, Silvia, Kunze, Catarina Alisa, Kulbe, Hagen, Sehouli, Jalid, Wienert, Stephan, Lindner, Judith, Budczies, Jan, Bockmayr, Michael, Dietel, Manfred, Denkert, Carsten, Braicu, Ioana, Jöhrens, Korinna
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4811475/
https://ncbi.nlm.nih.gov/pubmed/26625204
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