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Allicin Induces Calcium and Mitochondrial Dysregulation Causing Necrotic Death in Leishmania
BACKGROUND: Allicin has shown antileishmanial activity in vitro and in vivo. However the mechanism of action underlying its antiproliferative effect against Leishmania has been virtually unexplored. In this paper, we present the results obtained in L.infantum and a mechanistic basis is proposed. MET...
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| Pubblicato in: | PLoS Negl Trop Dis |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4811430/ https://ncbi.nlm.nih.gov/pubmed/27023069 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0004525 |
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