Ezetimibe Promotes Brush Border Membrane-to-Lumen Cholesterol Efflux in the Small Intestine

Ezetimibe inhibits Niemann-Pick C1-like 1 (NPC1L1), an apical membrane cholesterol transporter of enterocytes, thereby reduces intestinal cholesterol absorption. This treatment also increases extrahepatic reverse cholesterol transport via an undefined mechanism. To explore this, we employed a trans-...

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Bibliografski detalji
Izdano u:PLoS One
Glavni autori: Nakano, Takanari, Inoue, Ikuo, Takenaka, Yasuhiro, Ono, Hiraku, Katayama, Shigehiro, Awata, Takuya, Murakoshi, Takayuki
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2016
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4811413/
https://ncbi.nlm.nih.gov/pubmed/27023132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0152207
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