Lytic activity of the staphylolytic Twort phage endolysin CHAP domain is enhanced by the SH3b cell wall binding domain

Increases in the prevalence of antibiotic-resistant strains of Staphylococcus aureus have elicited efforts to develop novel antimicrobials to treat these drug-resistant pathogens. One potential treatment repurposes the lytic enzymes produced by bacteriophages as antimicrobials. The phage Twort endol...

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Publicat a:FEMS Microbiol Lett
Autors principals: Becker, Stephen C., Swift, Steven, Korobova, Olga, Schischkova, Nina, Kopylov, Pavel, Donovan, David M., Abaev, Igor
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2015
Matèries:
Research Letter
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4811206/
https://ncbi.nlm.nih.gov/pubmed/25790497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/femsle/fnu019
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