Dose-escalation study of octanoic acid in patients with essential tremor

BACKGROUND. Recently, 1-octanol has been shown to have efficacy in treating patients with essential tremor (ET). The primary metabolite of 1-octanol is octanoic acid (OA), which is now thought to be the active substance that mediates tremor suppression. Our aim was to describe the maximum tolerated...

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Bibliographic Details
Published in:J Clin Invest
Main Authors: Voller, Bernhard, Lines, Emily, McCrossin, Gayle, Tinaz, Sule, Lungu, Codrin, Grimes, George, Starling, Judith, Potti, Gopal, Buchwald, Peter, Haubenberger, Dietrich, Hallett, Mark
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 2016
Subjects:
Clinical Medicine
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4811161/
https://ncbi.nlm.nih.gov/pubmed/26927672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI83621
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