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Driving allotolerance: CAR-expressing Tregs for tolerance induction in organ and stem cell transplantation
Regulatory T cells (Tregs) modulate the function of a variety of immune cells and are critical for maintaining self-tolerance and preventing the development of autoimmune disease. Due to their ability to suppress effector T cells, Tregs have been increasingly explored for clinical use to suppress al...
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| Veröffentlicht in: | J Clin Invest |
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| 1. Verfasser: | |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Clinical Investigation
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4811145/ https://ncbi.nlm.nih.gov/pubmed/26999608 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI86827 |
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