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CCR7 and IRF4-dependent dendritic cells regulate lymphatic collecting vessel permeability

Lymphatic collecting vessels direct lymph into and from lymph nodes (LNs) and can become hyperpermeable as the result of a previous infection. Enhanced permeability has been implicated in compromised immunity due to reduced flow of lymph and immune cells to LNs, which are the primary site of antigen...

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Bibliografiske detaljer
Udgivet i:J Clin Invest
Main Authors: Ivanov, Stoyan, Scallan, Joshua P., Kim, Ki-Wook, Werth, Kathrin, Johnson, Michael W., Saunders, Brian T., Wang, Peter L., Kuan, Emma L., Straub, Adam C., Ouhachi, Melissa, Weinstein, Erica G., Williams, Jesse W., Briseño, Carlos, Colonna, Marco, Isakson, Brant E., Gautier, Emmanuel L., Förster, Reinhold, Davis, Michael J., Zinselmeyer, Bernd H., Randolph, Gwendalyn J.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4811132/
https://ncbi.nlm.nih.gov/pubmed/26999610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI84518
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