CCR7 and IRF4-dependent dendritic cells regulate lymphatic collecting vessel permeability

Lymphatic collecting vessels direct lymph into and from lymph nodes (LNs) and can become hyperpermeable as the result of a previous infection. Enhanced permeability has been implicated in compromised immunity due to reduced flow of lymph and immune cells to LNs, which are the primary site of antigen...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Ivanov, Stoyan, Scallan, Joshua P., Kim, Ki-Wook, Werth, Kathrin, Johnson, Michael W., Saunders, Brian T., Wang, Peter L., Kuan, Emma L., Straub, Adam C., Ouhachi, Melissa, Weinstein, Erica G., Williams, Jesse W., Briseño, Carlos, Colonna, Marco, Isakson, Brant E., Gautier, Emmanuel L., Förster, Reinhold, Davis, Michael J., Zinselmeyer, Bernd H., Randolph, Gwendalyn J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4811132/
https://ncbi.nlm.nih.gov/pubmed/26999610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI84518
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