Ovariectomy increases vascular calcification via the OPG/RANKL cytokine signalling pathway

BACKGROUND: Observational studies suggest a strong relationship between menopause and vascular calcification. Receptor activator of nuclear factor-κB ligand (RANKL) and osteoprotegerin (OPG) are critical regulators of bone remodelling and modulate vascular calcification. We assessed the hypothesis t...

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Udgivet i:Eur J Clin Invest
Main Authors: Choi, B. G., Vilahur, G., Cardoso, L., Fritton, J. C., Ibanez, B., Zafar, M. U., Yadegar, D., Speidl, W. S., Schaffler, M. B., Fuster, V., Badimon, J. J.
Format: Artigo
Sprog:Inglês
Udgivet: 2008
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4811027/
https://ncbi.nlm.nih.gov/pubmed/18279396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2362.2008.01930.x
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