WNT16-expressing Acute Lymphoblastic Leukemia Cells are Sensitive to Autophagy Inhibitors after ER Stress Induction

BACKGROUND: Previous work from our group showed hypoxia can induce endoplasmic reticulum (ER) stress and block the processing of the WNT3 protein in cells engineered to express WNT3a. Acute lymphoblastic leukemia (ALL) cells with the t(1:19) translocation express the WNT16 gene, which is thought to...

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Bibliographic Details
Published in:Anticancer Res
Main Authors: Verras, Meletios, Papandreou, Ioanna, Denko, Nicholas C.
Format: Artigo
Language:Inglês
Published: 2015
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4810683/
https://ncbi.nlm.nih.gov/pubmed/26254351
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