Identifying panaxynol, a natural activator of nuclear factor erythroid-2 related factor 2 (Nrf2) from American ginseng as a suppressor of inflamed macrophage-induced cardiomyocyte hypertrophy

ETHNOPHARMACOLOGICAL RELEVANCE: American ginseng is capable of ameliorating cardiac dysfunction and activating Nrf2, a master regulator of antioxidant defense, in the heart. This study was designed to isolate compounds from American ginseng and to determine those responsible for the Nrf2-mediated re...

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Gepubliceerd in:J Ethnopharmacol
Hoofdauteurs: Qu, Chen, Li, Bin, Lai, Yimu, Li, Hechu, Windust, Anthony, Hofseth, Lorne J., Nagarkatti, Mitzi, Nagarkatti, Prakash, Wang, Xing Li, Tang, Dongqi, Janicki, Joseph S., Tian, Xingsong, Cui, Taixing
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2015
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4810680/
https://ncbi.nlm.nih.gov/pubmed/25882312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jep.2015.04.004
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