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Characterization of Antibody Bipolar Bridging Mediated by the Human Cytomegalovirus Fc Receptor gp68

The human cytomegalovirus glycoprotein gp68 functions as an Fc receptor for host IgGs and can form antibody bipolar bridging (ABB) complexes in which gp68 binds the Fc region of an antigen-bound IgG. Here we show that gp68-mediated endocytosis transports ABB complexes into endosomes, after which the...

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Foilsithe in:J Virol
Main Authors: Ndjamen, Blaise, Joshi, Devashish S., Fraser, Scott E., Bjorkman, Pamela J.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology 2016
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4810659/
https://ncbi.nlm.nih.gov/pubmed/26739053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02855-15
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