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Human Cytomegalovirus US28 Is Important for Latent Infection of Hematopoietic Progenitor Cells

Human cytomegalovirus (HCMV) resides latently in hematopoietic progenitor cells (HPCs). During latency, only a subset of HCMV genes is transcribed, including one of the four virus-encoded G protein-coupled receptors (GPCRs), US28. Although US28 is a multifunctional lytic protein, its function during...

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Bibliographic Details
Published in:J Virol
Main Authors: Humby, Monica S., O'Connor, Christine M.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4810657/
https://ncbi.nlm.nih.gov/pubmed/26719258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02507-15
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