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Membrane Perturbation-Associated Ca(2+) Signaling and Incoming Genome Sensing Are Required for the Host Response to Low-Level Enveloped Virus Particle Entry

The type I interferon (IFN) response is an important aspect of innate antiviral defense, and the transcription factor IRF3 plays an important role in its induction. Membrane perturbation during fusion, a necessary step for enveloped virus particle entry, appears sufficient to induce transcription of...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Hare, David N., Collins, Susan E., Mukherjee, Subhendu, Loo, Yueh-Ming, Gale, Michael, Janssen, Luke J., Mossman, Karen L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4810640/
https://ncbi.nlm.nih.gov/pubmed/26719279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02642-15
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