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ISC, a Novel Group of Bacterial and Archaeal DNA Transposons That Encode Cas9 Homologs

Bacterial genomes encode numerous homologs of Cas9, the effector protein of the type II CRISPR-Cas systems. The homology region includes the arginine-rich helix and the HNH nuclease domain that is inserted into the RuvC-like nuclease domain. These genes, however, are not linked to cas genes or CRISP...

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Vydáno v:J Bacteriol
Hlavní autoři: Kapitonov, Vladimir V., Makarova, Kira S., Koonin, Eugene V.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4810608/
https://ncbi.nlm.nih.gov/pubmed/26712934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00783-15
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