The Tangier disease gene product ABC1 controls the cellular apolipoprotein-mediated lipid removal pathway

The ABC1 transporter was identified as the defect in Tangier disease by a combined strategy of gene expression microarray analysis, genetic mapping, and biochemical studies. Patients with Tangier disease have a defect in cellular cholesterol removal, which results in near zero plasma levels of HDL a...

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Библиографические подробности
Главные авторы: Lawn, Richard M., Wade, David P., Garvin, Michael R., Wang, Xingbo, Schwartz, Karen, Porter, J. Gordon, Seilhamer, Jeffrey J., Vaughan, Ashley M., Oram, John F.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Clinical Investigation 1999
Предметы:
Rapid Publication
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC481052/
https://ncbi.nlm.nih.gov/pubmed/10525055
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