An Outer Mitochondrial Translocase, Tom22, Is Crucial for Inner Mitochondrial Steroidogenic Regulation in Adrenal and Gonadal Tissues

After cholesterol is transported into the mitochondria of steroidogenic tissues, the first steroid, pregnenolone, is synthesized in adrenal and gonadal tissues to initiate steroid synthesis by catalyzing the conversion of pregnenolone to progesterone, which is mediated by the inner mitochondrial enz...

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Bibliographic Details
Published in:Mol Cell Biol
Main Authors: Rajapaksha, Maheshinie, Kaur, Jasmeet, Prasad, Manoj, Pawlak, Kevin J., Marshall, Brendan, Perry, Elizabeth W., Whittal, Randy M., Bose, Himangshu S.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2016
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4810470/
https://ncbi.nlm.nih.gov/pubmed/26787839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01107-15
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