Yüklüyor......
Fast antibody fragment motion: flexible linkers act as entropic spring
A flexible linker region between three fragments allows antibodies to adjust their binding sites to an antigen or receptor. Using Neutron Spin Echo Spectroscopy we observed fragment motion on a timescale of 7 ns with motional amplitudes of about 1 nm relative to each other. The mechanistic complexit...
Kaydedildi:
| Yayımlandı: | Sci Rep |
|---|---|
| Asıl Yazarlar: | , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Nature Publishing Group
2016
|
| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4810366/ https://ncbi.nlm.nih.gov/pubmed/27020739 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep22148 |
| Etiketler: |
Etiketle
Etiket eklenmemiş, İlk siz ekleyin!
|