G3BP–Caprin1–USP10 complexes mediate stress granule condensation and associate with 40S subunits

Mammalian stress granules (SGs) contain stalled translation preinitiation complexes that are assembled into discrete granules by specific RNA-binding proteins such as G3BP. We now show that cells lacking both G3BP1 and G3BP2 cannot form SGs in response to eukaryotic initiation factor 2α phosphorylat...

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Vydáno v:J Cell Biol
Hlavní autoři: Kedersha, Nancy, Panas, Marc D., Achorn, Christopher A., Lyons, Shawn, Tisdale, Sarah, Hickman, Tyler, Thomas, Marshall, Lieberman, Judy, McInerney, Gerald M., Ivanov, Pavel, Anderson, Paul
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2016
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Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4810302/
https://ncbi.nlm.nih.gov/pubmed/27022092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201508028
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