PhTx3-4, a Spider Toxin Calcium Channel Blocker, Reduces NMDA-Induced Injury of the Retina

The in vivo neuroprotective effect of PhTx3-4, a spider toxin N-P/Q calcium channel blocker, was studied in a rat model of NMDA-induced injury of the retina. NMDA (N-Methyl-d-Aspartate)-induced retinal injury in rats reduced the b-wave amplitude by 62% ± 3.6%, indicating the severity of the insult....

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Publicat a:Toxins (Basel)
Autors principals: Binda, Nancy Scardua, Porto Petruceli Carayon, Charles, Agostini, Rafael Mourão, do Nascimento Pinheiro, Ana Cristina, Nascimento Cordeiro, Marta, Romano Silva, Marco Aurélio, Figueira Silva, Juliana, Rita Pereira, Elizete Maria, da Silva Junior, Claudio Antonio, de Castro Junior, Célio José, Sena Guimarães, Andre Luiz, Gomez, Marcus Vinicius
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2016
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4810215/
https://ncbi.nlm.nih.gov/pubmed/26978403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins8030070
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