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Knockdown of fast skeletal myosin-binding protein C in zebrafish results in a severe skeletal myopathy
Myosin-binding protein C (MyBPC) in the muscle sarcomere interacts with several contractile and structural proteins. Mutations in the cardiac isoform (MyBPC-3) in humans, or animal knockout, are associated with cardiomyopathy. Function of the fast skeletal isoform (MyBPC-2) in living muscles is less...
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| Publicado no: | J Gen Physiol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4810067/ https://ncbi.nlm.nih.gov/pubmed/27022191 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201511452 |
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