Depletion of Human DNA in Spiked Clinical Specimens for Improvement of Sensitivity of Pathogen Detection by Next-Generation Sequencing

Next-generation sequencing (NGS) technology has shown promise for the detection of human pathogens from clinical samples. However, one of the major obstacles to the use of NGS in diagnostic microbiology is the low ratio of pathogen DNA to human DNA in most clinical specimens. In this study, we aimed...

Cur síos iomlán

Na minha lista:
Sonraí Bibleagrafaíochta
Foilsithe in:J Clin Microbiol
Main Authors: Hasan, Mohammad R., Rawat, Arun, Tang, Patrick, Jithesh, Puthen V., Thomas, Eva, Tan, Rusung, Tilley, Peter
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology 2016
Ábhair:
Bacteriology
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4809942/
https://ncbi.nlm.nih.gov/pubmed/26763966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.03050-15
Clibeanna: Cuir Clib Leis
Gan Chlibeanna, Bí ar an gcéad duine leis an taifead seo a chlibeáil!

Míreanna Comhchosúla